Blar i forfatter "Stensen, Wenche"

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    • Anti-Colonization Effect of Au Surfaces with Self-Assembled Molecular Monolayers Functionalized with Antimicrobial Peptides on S. epidermidis 

      Karlsen, Eskil André; Stensen, Wenche; Juskewitz, Eric; Svenson, Johan; Berglin, Mattias; Svendsen, John Sigurd Mjøen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-10)
      Medical devices with an effective anti-colonization surface are important tools for combatting healthcare-associated infections. Here, we investigated the anti-colonization efficacy of antimicrobial peptides covalently attached to a gold model surface. The gold surface was modified by a self-assembled polyethylene glycol monolayer with an acetylene terminus. The peptides were covalently connected ...

    • Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome 

      Stensen, Wenche; Rothweiler, Ulli; Engh, Richard Alan; Stasko, Melissa R.; Bederman, Ilya; Costa, Alberto C. S.; Fugelli, Anders; Svendsen, John Sigurd Mjøen (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-17)
      Down syndrome (DS) is a complex genetic disorder associated with substantial physical, cognitive, and behavioral challenges. Due to better treatment options for the physical co-morbidities of DS, the life expectancy of individuals with DS is beginning to approach that of the general population. However, the cognitive deficits seen in individuals with DS still cannot be addressed pharmacologically. ...